Anterior cervical discectomy and fusion with recombinant human bone morphogenetic protein-2-adsorbed β-tricalcium phosphate granules: a preliminary report

Background: Anterior cervical discectomy and fusion (ACDF) is a substitute for conservative remedy within the therapy of cervical spondylopathy. This examine evaluated the medical final result of ACDF with BMP-2-adsorbed β-tricalcium phosphate granules.

 

Strategies: Thirty-two sufferers with cervical spondylopathy acquired therapy of ACDF with BMP-2-adsorbed β-tricalcium phosphate granules. The medical outcomes have been evaluated with the Japanese Orthopedic Affiliation (JOA) scores and Neck Incapacity Index (NDI). In the meantime, the cervical curvature and intervertebral heights have been obtained via lateral cervical X-ray movies pre- and postoperatively at every interval, and the precision of cervical fusion was assessed by three-dimensional computed tomography scan.

 

Outcomes: The follow-up averaged 15.2 months (vary 13-18). Common JOA scores considerably elevated from a preoperative level (7.4 ± 1.2) to every interval after surgical procedure (P < 0.05). NDI decreased from preoperative level (43.1 ± 9.0) to every interval after surgical procedure (P < 0.05). The angles of cervical curvature and intervertebral heights have been improved postoperatively and saved all through the follow-up interval. CT scan demonstrated a fusion fee of 82.9% at 6 months postoperatively and was improved to 100% at 12 months postoperatively. In all instances, no problems appeared and reported resulting from any lapse in surgical process expertise all through the follow-up interval.

 

Conclusions: Our preliminary findings recommend that BMP-2-adsorbed β-tricalcium phosphate granules will probably be an efficient various to autogenous bone grafting for cervical fusion in treating cervical spondylopathy. Our surgical process usingβ-tricalcium phosphate granules may enhance neurological operate, get better intervertebral peak and cervical curvature, and could possibly be probably exploitable within the medical setting.
Genoimmun
                                                                         Genoimmun

 

Key phrases: Anterior cervical discectomy and fusion; Bone morphogenetic protein-2; β-tricalcium phosphate.

 

Human Cpn10 Protein

SPR-310B 0.1 mg
EUR 393
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: Untagged recombinant human Cpn10 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.

Human Cpn10 Protein

SPR-310C 2x0.1 mg
EUR 665
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: Untagged recombinant human Cpn10 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.

Cpn10 Antibody

49935-100ul 100ul
EUR 333

Cpn10 Antibody

49935-50ul 50ul
EUR 239

Human CPN10 ELISA Kit

EHC0822 96Tests
EUR 521

Antibody for Human Cpn10

SPC-193C 0.025mg
EUR 180
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is unconjugated.

Antibody for Human Cpn10

SPC-193D 0.1mg
EUR 276
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is unconjugated.

Antibody for Human Cpn10

SPC-193D-A390 0.1mg
EUR 323
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 390.

Antibody for Human Cpn10

SPC-193D-A488 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 488.

Antibody for Human Cpn10

SPC-193D-A565 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 565.

Antibody for Human Cpn10

SPC-193D-A594 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 594.

Antibody for Human Cpn10

SPC-193D-A633 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 633.

Antibody for Human Cpn10

SPC-193D-A655 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 655.

Antibody for Human Cpn10

SPC-193D-A680 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 680.

Antibody for Human Cpn10

SPC-193D-A700 0.1mg
EUR 322
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 700.

Antibody for Human Cpn10

SPC-193D-ALP 0.1mg
EUR 316
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human Cpn10

SPC-193D-APC 0.1mg
EUR 321
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to APC .

Antibody for Human Cpn10

SPC-193D-APCCY7 0.1mg
EUR 394
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to APC/Cy7.

Antibody for Human Cpn10

SPC-193D-BI 0.1mg
EUR 318
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Biotin.

Antibody for Human Cpn10

SPC-193D-DY350 0.1mg
EUR 337
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Dylight 350.

Antibody for Human Cpn10

SPC-193D-DY405 0.1mg
EUR 325
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Dylight 405.

Antibody for Human Cpn10

SPC-193D-DY488 0.1mg
EUR 315
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Dylight 488.

Antibody for Human Cpn10

SPC-193D-DY594 0.1mg
EUR 317
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Dylight 594.

Antibody for Human Cpn10

SPC-193D-DY633 0.1mg
EUR 312
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Dylight 633.

Antibody for Human Cpn10

SPC-193D-FITC 0.1mg
EUR 314
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to FITC.

Antibody for Human Cpn10

SPC-193D-HRP 0.1mg
EUR 310
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to HRP.

Antibody for Human Cpn10

SPC-193D-P594 0.1mg
EUR 329
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to PE/ATTO 594.

Antibody for Human Cpn10

SPC-193D-PCP 0.1mg
EUR 321
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to PerCP.

Antibody for Human Cpn10

SPC-193D-RPE 0.1mg
EUR 319
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to RPE .

Antibody for Human Cpn10

SPC-193D-STR 0.1mg
EUR 320
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to Streptavidin.

Antibody for Human Cpn10

SPC-193S 0.012mg
EUR 65
  • Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (HSP10s). Cpn10 acts as a co-chaperone and interacts with the HSP60 family to promote proper folding
  • Show more
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is unconjugated.

Cpn10 Conjugated Antibody

C49935 100ul
EUR 397

Goat CPN10 ELISA Kit

EGTC0822 96Tests
EUR 521

Bovine CPN10 ELISA Kit

EBC0822 96Tests
EUR 521

Canine CPN10 ELISA Kit

ECC0822 96Tests
EUR 521

Anserini CPN10 ELISA Kit

EAC0822 96Tests
EUR 521

Chaperonin 10 (CPN10) Antibody

abx430356-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Chaperonin 10 (CPN10) Antibody

abx430357-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Chaperonin 10 (Cpn10) Antibody

20-abx445145
  • EUR 425.00
  • EUR 314.00
  • 100 ug
  • 25 ug
  • Shipped within 5-12 working days.

Mouse CPN10 ELISA Kit

EMC0822 96Tests
EUR 521

Rat CPN10 ELISA Kit

ERC0822 96Tests
EUR 521

Rabbit CPN10 ELISA Kit

ERTC0822 96Tests
EUR 521

Porcine CPN10 ELISA Kit

EPC0822 96Tests
EUR 521

Anti-Cpn10/HSPE1 Antibody

PA1790 100ug/vial
EUR 294

Anti-CPN10 / HSPE1 antibody

STJ73151 100 µg
EUR 359

Human chaperonin 10,CPN10 ELISA Kit

201-12-0674 96 tests
EUR 440
  • This chaperonin 10 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Chaperonin 10 (CPN10) ELISA Kit

abx052001-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Human chaperonin 10,CPN10 ELISA Kit

CN-03950H1 96T
EUR 464

 

In vitro therapy of three T3-L1 adipocytes with recombinant Calcium/calmodulin-dependent Protein Kinase IV (CaMKIV) limits ER stress and improves insulin sensitivity via inhibition of autophagy through the mTOR/CREB signaling pathway

 

Background: Lately, CaMKIV has been recognized as a possible regulator of skeletal muscle glucose metabolism, it will possibly additionally have an effect on insulin gene expression in pancreas. Nonetheless, its results on adipose insulin resistance have but to be explored. Autophagy has been proven as a possible therapeutic goal for ER (endoplasmic reticulum) stress and insulin resistance. The aim of this examine is to research the consequences of CaMKIV on ER stress, autophagic operate and insulin signaling in tunicamycin-treated adipocytes.

 

Strategies: On this examine, mature three T3-L1 adipocytes have been handled with tunicamycin to induce ER stress. Tunicamycin-treated three T3-L1 adipocytes have been handled with recombinant CaMKIV within the presence or absence of targeted-siRNA mediated down-regulation of CREB and mTOR. The ER stress markers, autophagy activation, mTOR/CREB signaling and insulin sensitivity have been analyzed by western blotting or electron microscopy.

 

Outcomes: Remedy with CaMKIV considerably reversed tunicamycin-induced expression of p-PERK, cleaved-ATF6, Atg7 and LC3II. It additionally diminished p62 expression. As well as, ranges of p-Akt and p-IRS-1 have been elevated. Furthermore, CaMKIV inhibited activated ER stress and insulin resistance in Atg7 siRNA transfected adipocytes. Nonetheless, the protecting results of CaMKIV on ER stress, insulin signaling, and autophagy operate have been nullified by suppression of mTOR or CREB in tunicamycin-treated adipocytes.

 

Conclusion: This examine proves recombinant CaMKIV inhibits tunicamycin-induced ER stress and insulin resistance by regulating autophagy. The protecting impact of CaMKIV in adipocytes is affected not less than partly via mTOR/CREB signaling. Our discovering could supply novel alternatives for treating weight problems and kind 2 diabetes.

 

Key phrases: Adipose; Autophagy; CaMKIV; ER stress; Insulin resistance.

 

One-step heating technique for environment friendly solubilization of recombinant spider silk protein from inclusion our bodies

 

Background: Spider silk is a proteinaceous fiber with outstanding mechanical properties spun from spider silk proteins (spidroins). Engineering spidroins have been efficiently produced in quite a lot of heterologous hosts and probably the most broadly used expression system is Escherichia coli (E. coli).

 

To this point, recombinantly expressed spidroins usually kind insoluble inclusion our bodies (IBs), which can usually be dissolved beneath extraordinarily harsh situations in a standard method, e.g. both Eight mol/L urea or 6 mol/L guanidine hydrochloride, extremely risking to poor restoration of bioactive proteins in addition to sudden precipitations throughout dialysis course of.

 

Outcomes: Right here, we current a gentle solubilization strategy-one-step heating methodology to solubilize spidroins from IBs, with combining spidroins’ excessive thermal stability with low focus of urea. A 430-aa recombinant protein (designated as NM) derived from the minor ampullate spidroin of Araneus ventricosus was expressed in E. coli, and the recombinant proteins have been primarily current in insoluble fraction as IBs.

 

The remoted IBs have been solubilized parallelly by each conventional urea-denatured methodology and one-step heating methodology, respectively. The solubilization effectivity of NM IBs in Tris-HCl pH 8.Zero containing Four mol/L urea by one-step heating methodology was already akin to that of seven mol/L urea with utilizing conventional urea-denatured methodology.

 

The results of buffer, pH and temperature situations on NM IBs solubilization of one-step heating methodology have been evaluated, respectively, primarily based on which the beneficial situations are: heating temperature 70-90 °C for 20 min, pH 7.0-10, urea focus 2-Four mol/L in regular organic buffers.

 

The recombinant NM generated through the one-step heating methodology held the potential features with self-assembling into sphere nanoparticles with easy morphology.

 

Conclusions: The one-step heating methodology launched right here effectively solubilizes IBs beneath comparatively delicate situations in comparison with the standard ones, which is perhaps essential for the downstream functions; nonetheless, this protocol needs to be pursued fastidiously when it comes to urea-induced modification delicate functions.

 

Additional, this methodology will be utilized beneath broad buffer, pH and temperature situations, conferring the potential to use to different thermal steady proteins.

 

Key phrases: Heating; Inclusion physique solubilization; NM IBs; Recombinant spidroin.

GRP78 BiP Antibody

48115-100ul 100ul
EUR 333

GRP78 BiP Antibody

48115-50ul 50ul
EUR 239

GRP78 BiP Antibody

48119-100ul 100ul
EUR 333

GRP78 BiP Antibody

48119-50ul 50ul
EUR 239

GRP78 Bip Antibody

39220-100ul 100ul
EUR 390

GRP78 BiP Antibody

abx038413-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

GRP78 / BIP Antibody

abx233662-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

anti-GRP78 BiP

YF-PA23927 50 ul
EUR 334
Description: Mouse polyclonal to GRP78 BiP

Active Human GRP78 (Bip) Protein

SPR-107A 0.05 mg
EUR 201
  • GRP78 is a ubiquitously expressed, 78-kDa glucose-regulated protein, and is commonly referred to as an immunoglobin chain binding protein (BiP). The BiP proteins are categorized as stress response proteins because they play an important role in the p
  • Show more
Description: His tagged recombinant human GRP78 (Bip) Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human GRP78 (Bip) Protein

SPR-107B 0.1 mg
EUR 320
  • GRP78 is a ubiquitously expressed, 78-kDa glucose-regulated protein, and is commonly referred to as an immunoglobin chain binding protein (BiP). The BiP proteins are categorized as stress response proteins because they play an important role in the p
  • Show more
Description: His tagged recombinant human GRP78 (Bip) Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

Active Human GRP78 (Bip) Protein

SPR-107C 2x0.1 mg
EUR 538
  • GRP78 is a ubiquitously expressed, 78-kDa glucose-regulated protein, and is commonly referred to as an immunoglobin chain binding protein (BiP). The BiP proteins are categorized as stress response proteins because they play an important role in the p
  • Show more
Description: His tagged recombinant human GRP78 (Bip) Protein expressed in E. coli for WB, SDS-PAGE, ATPase Activity Assay, Functional Assay, ELISA. This protein is biologically active (ATPase active).

GRP78 / BiP Polyclonal Antibody

27530-100ul 100ul
EUR 252

GRP78 / BiP Polyclonal Antibody

27530-50ul 50ul
EUR 187

GRP78 / BiP Polyclonal Antibody

27540-100ul 100ul
EUR 252

GRP78 / BiP Polyclonal Antibody

27540-50ul 50ul
EUR 187

GRP78 / BiP Rabbit pAb

A11366-100ul 100 ul
EUR 308

GRP78 / BiP Rabbit pAb

A11366-200ul 200 ul
EUR 459

GRP78 / BiP Rabbit pAb

A11366-20ul 20 ul
EUR 183

GRP78 / BiP Rabbit pAb

A11366-50ul 50 ul
EUR 223

GRP78 / BiP Rabbit pAb

A11568-100ul 100 ul
EUR 308

GRP78 / BiP Rabbit pAb

A11568-200ul 200 ul
EUR 459

GRP78 / BiP Rabbit pAb

A11568-20ul 20 ul
EUR 183

GRP78 / BiP Rabbit pAb

A11568-50ul 50 ul
EUR 223

GRP78 / BiP Rabbit pAb

A0241-100ul 100 ul
EUR 308

GRP78 / BiP Rabbit pAb

A0241-200ul 200 ul
EUR 459

GRP78 / BiP Rabbit pAb

A0241-20ul 20 ul
EUR 183

GRP78 / BiP Rabbit pAb

A0241-50ul 50 ul
EUR 223

GRP78 BiP Conjugated Antibody

C48115 100ul
EUR 397

GRP78 (Bip) Antibody (Biotin)

abx445644-100ug 100 ug
EUR 537
  • Shipped within 5-12 working days.

GRP78 (Bip) Antibody (FITC)

abx445645-100ug 100 ug
EUR 537
  • Shipped within 5-12 working days.

GRP78 (Bip) Antibody (HRP)

abx445646-100ug 100 ug
EUR 537
  • Shipped within 5-12 working days.

GRP78/Bip Monoclonal Antibody

ABM40213-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of GRP78/Bip from Human, Rat. This GRP78/Bip antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

GRP78/Bip Monoclonal Antibody

ABM40213-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of GRP78/Bip from Human, Rat. This GRP78/Bip antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

GRP78/Bip Monoclonal Antibody

ABM40213-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of GRP78/Bip from Human, Rat. This GRP78/Bip antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

GRP78/Bip Monoclonal Antibody

ABM40216-003ml 0.03ml
EUR 158
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of GRP78/Bip from Human, Rat. This GRP78/Bip antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

GRP78/Bip Monoclonal Antibody

ABM40216-01ml 0.1ml
EUR 289
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of GRP78/Bip from Human, Rat. This GRP78/Bip antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

GRP78/Bip Monoclonal Antibody

ABM40216-02ml 0.2ml
EUR 414
  • Immunogen information: Synthetic Peptide
  • Applications tips:
Description: A monoclonal antibody for detection of GRP78/Bip from Human, Rat. This GRP78/Bip antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen synthetic peptide

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