Anterior cervical discectomy and fusion with recombinant human bone morphogenetic protein-2-adsorbed β-tricalcium phosphate granules: a preliminary report

Background: Anterior cervical discectomy and fusion (ACDF) is a substitute for conservative remedy within the therapy of cervical spondylopathy. This examine evaluated the medical final result of ACDF with BMP-2-adsorbed β-tricalcium phosphate granules.

 

Strategies: Thirty-two sufferers with cervical spondylopathy acquired therapy of ACDF with BMP-2-adsorbed β-tricalcium phosphate granules. The medical outcomes have been evaluated with the Japanese Orthopedic Affiliation (JOA) scores and Neck Incapacity Index (NDI). In the meantime, the cervical curvature and intervertebral heights have been obtained via lateral cervical X-ray movies pre- and postoperatively at every interval, and the precision of cervical fusion was assessed by three-dimensional computed tomography scan.

 

Outcomes: The follow-up averaged 15.2 months (vary 13-18). Common JOA scores considerably elevated from a preoperative level (7.4 ± 1.2) to every interval after surgical procedure (P < 0.05). NDI decreased from preoperative level (43.1 ± 9.0) to every interval after surgical procedure (P < 0.05). The angles of cervical curvature and intervertebral heights have been improved postoperatively and saved all through the follow-up interval. CT scan demonstrated a fusion fee of 82.9% at 6 months postoperatively and was improved to 100% at 12 months postoperatively. In all instances, no problems appeared and reported resulting from any lapse in surgical process expertise all through the follow-up interval.

 

Conclusions: Our preliminary findings recommend that BMP-2-adsorbed β-tricalcium phosphate granules will probably be an efficient various to autogenous bone grafting for cervical fusion in treating cervical spondylopathy. Our surgical process usingβ-tricalcium phosphate granules may enhance neurological operate, get better intervertebral peak and cervical curvature, and could possibly be probably exploitable within the medical setting.
Genoimmun
                                                                         Genoimmun

 

Key phrases: Anterior cervical discectomy and fusion; Bone morphogenetic protein-2; β-tricalcium phosphate.

 

Human Cpn10 Protein

SPR-310A 0.05 mg
EUR 313.2
Description: Untagged recombinant human Cpn10 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.

Human Cpn10 Protein

SPR-310B 0.1 mg
EUR 471.6
Description: Untagged recombinant human Cpn10 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.

Human Cpn10 Protein

SPR-310C 2x0.1 mg
EUR 798
Description: Untagged recombinant human Cpn10 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.

CPNE1 Recombinant Protein (Human)

RP007876 100 ug Ask for price

CPNE2 Recombinant Protein (Human)

RP007879 100 ug Ask for price

CPNE3 Recombinant Protein (Human)

RP007882 100 ug Ask for price

CPNE3 Recombinant Protein (Human)

RP007885 100 ug Ask for price

CPNE4 Recombinant Protein (Human)

RP007888 100 ug Ask for price

CPNE5 Recombinant Protein (Human)

RP007891 100 ug Ask for price

CPNE6 Recombinant Protein (Human)

RP007894 100 ug Ask for price

CPNE7 Recombinant Protein (Human)

RP007897 100 ug Ask for price

CPNE8 Recombinant Protein (Human)

RP038266 100 ug Ask for price

CPNE9 Recombinant Protein (Human)

RP038269 100 ug Ask for price

CPN1 Recombinant Protein (Rat)

RP196112 100 ug Ask for price

CPN2 Recombinant Protein (Rat)

RP196115 100 ug Ask for price

CPN1 Recombinant Protein (Mouse)

RP125759 100 ug Ask for price

CPN2 Recombinant Protein (Mouse)

RP125762 100 ug Ask for price

Recombinant Chlamydophila Pneumoniae CPn_0129/CPn_0130 Protein (aa 1-394)

VAng-Lsx2741-inquire inquire Ask for price
Description: Chlamydophila Pneumoniae Uncharacterized protein CPn_0129/CPn_0130/CP_0642/CPj0130/CpB0131, recombinant protein.

Recombinant Chlamydophila Pneumoniae CPn_0344 Protein (aa 1-621)

VAng-Lsx2746-inquire inquire Ask for price
Description: Chlamydophila Pneumoniae Putative zinc metalloprotease CPn_0344/CP_0416/CPj0344/CpB0350, recombinant protein.

CPNE1 Recombinant Protein (Rat)

RP196118 100 ug Ask for price

CPNE3 Recombinant Protein (Rat)

RP196121 100 ug Ask for price

CPNE4 Recombinant Protein (Rat)

RP196124 100 ug Ask for price

CPNE5 Recombinant Protein (Rat)

RP196127 100 ug Ask for price

CPNE6 Recombinant Protein (Rat)

RP196130 100 ug Ask for price

CPNE7 Recombinant Protein (Rat)

RP196133 100 ug Ask for price

CPNE8 Recombinant Protein (Rat)

RP196136 100 ug Ask for price

CPNE9 Recombinant Protein (Rat)

RP196139 100 ug Ask for price

CPNE1 Recombinant Protein (Mouse)

RP125765 100 ug Ask for price

CPNE1 Recombinant Protein (Mouse)

RP125768 100 ug Ask for price

CPNE2 Recombinant Protein (Mouse)

RP125771 100 ug Ask for price

CPNE3 Recombinant Protein (Mouse)

RP125774 100 ug Ask for price

CPNE4 Recombinant Protein (Mouse)

RP125777 100 ug Ask for price

CPNE5 Recombinant Protein (Mouse)

RP125780 100 ug Ask for price

CPNE6 Recombinant Protein (Mouse)

RP125783 100 ug Ask for price

CPNE6 Recombinant Protein (Mouse)

RP125786 100 ug Ask for price

CPNE6 Recombinant Protein (Mouse)

RP125789 100 ug Ask for price

CPNE7 Recombinant Protein (Mouse)

RP125792 100 ug Ask for price

CPNE8 Recombinant Protein (Mouse)

RP125795 100 ug Ask for price

CPNE8 Recombinant Protein (Mouse)

RP125798 100 ug Ask for price

CPNE9 Recombinant Protein (Mouse)

RP125801 100 ug Ask for price

Recombinant Plasmodium Falciparum Chaperonin CPN60, mitochondrial, Protein (aa 1-700)

VAng-Wyb6378-inquire inquire Ask for price
Description: Plasmodium Falciparum (isolate FCR-3 / Gambia) Chaperonin CPN60, mitochondrial, recombinant protein.

Recombinant (E.Coli) purified Mycobacterium Tuberculosis Heat Shock Protein 65 (hsp65/groEL-2/Cpn60-2)

RP-627 10 ug
EUR 343.2

Recombinant purified M. tuberculosis Heat Shock Protein 65 (hsp65/groEL-2/Cpn60-2) control for Western

HSP651-C 100 ul
EUR 343.2

Human CPN10 ELISA Kit

EHC0822 96Tests
EUR 625.2

Antibody for Human Cpn10

SPC-193C 0.025mg
EUR 216
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is unconjugated.

Antibody for Human Cpn10

SPC-193D 0.1mg
EUR 331.2
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is unconjugated.

Antibody for Human Cpn10

SPC-193D-A390 0.1mg
EUR 387.6
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 390.

Antibody for Human Cpn10

SPC-193D-A488 0.1mg
EUR 386.4
Description: A polyclonal antibody for Cpn10 from Human | Mouse | Rat | Bovine | Dog | Guinea Pig (Cavia porcellus) | Pig | rabbit | Sheep | African clawed frog (Xenopus laevis). The antibody is produced in rabbit after immunization with human Cpn10 peptide AA 91-101. The Antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100). This Cpn10 antibody is conjugated to ATTO 488.

 

In vitro therapy of three T3-L1 adipocytes with recombinant Calcium/calmodulin-dependent Protein Kinase IV (CaMKIV) limits ER stress and improves insulin sensitivity via inhibition of autophagy through the mTOR/CREB signaling pathway

 

Background: Lately, CaMKIV has been recognized as a possible regulator of skeletal muscle glucose metabolism, it will possibly additionally have an effect on insulin gene expression in pancreas. Nonetheless, its results on adipose insulin resistance have but to be explored. Autophagy has been proven as a possible therapeutic goal for ER (endoplasmic reticulum) stress and insulin resistance. The aim of this examine is to research the consequences of CaMKIV on ER stress, autophagic operate and insulin signaling in tunicamycin-treated adipocytes.

 

Strategies: On this examine, mature three T3-L1 adipocytes have been handled with tunicamycin to induce ER stress. Tunicamycin-treated three T3-L1 adipocytes have been handled with recombinant CaMKIV within the presence or absence of targeted-siRNA mediated down-regulation of CREB and mTOR. The ER stress markers, autophagy activation, mTOR/CREB signaling and insulin sensitivity have been analyzed by western blotting or electron microscopy.

 

Outcomes: Remedy with CaMKIV considerably reversed tunicamycin-induced expression of p-PERK, cleaved-ATF6, Atg7 and LC3II. It additionally diminished p62 expression. As well as, ranges of p-Akt and p-IRS-1 have been elevated. Furthermore, CaMKIV inhibited activated ER stress and insulin resistance in Atg7 siRNA transfected adipocytes. Nonetheless, the protecting results of CaMKIV on ER stress, insulin signaling, and autophagy operate have been nullified by suppression of mTOR or CREB in tunicamycin-treated adipocytes.

 

Conclusion: This examine proves recombinant CaMKIV inhibits tunicamycin-induced ER stress and insulin resistance by regulating autophagy. The protecting impact of CaMKIV in adipocytes is affected not less than partly via mTOR/CREB signaling. Our discovering could supply novel alternatives for treating weight problems and kind 2 diabetes.

 

Key phrases: Adipose; Autophagy; CaMKIV; ER stress; Insulin resistance.

 

One-step heating technique for environment friendly solubilization of recombinant spider silk protein from inclusion our bodies

 

Background: Spider silk is a proteinaceous fiber with outstanding mechanical properties spun from spider silk proteins (spidroins). Engineering spidroins have been efficiently produced in quite a lot of heterologous hosts and probably the most broadly used expression system is Escherichia coli (E. coli).

 

To this point, recombinantly expressed spidroins usually kind insoluble inclusion our bodies (IBs), which can usually be dissolved beneath extraordinarily harsh situations in a standard method, e.g. both Eight mol/L urea or 6 mol/L guanidine hydrochloride, extremely risking to poor restoration of bioactive proteins in addition to sudden precipitations throughout dialysis course of.

 

Outcomes: Right here, we current a gentle solubilization strategy-one-step heating methodology to solubilize spidroins from IBs, with combining spidroins’ excessive thermal stability with low focus of urea. A 430-aa recombinant protein (designated as NM) derived from the minor ampullate spidroin of Araneus ventricosus was expressed in E. coli, and the recombinant proteins have been primarily current in insoluble fraction as IBs.

 

The remoted IBs have been solubilized parallelly by each conventional urea-denatured methodology and one-step heating methodology, respectively. The solubilization effectivity of NM IBs in Tris-HCl pH 8.Zero containing Four mol/L urea by one-step heating methodology was already akin to that of seven mol/L urea with utilizing conventional urea-denatured methodology.

 

The results of buffer, pH and temperature situations on NM IBs solubilization of one-step heating methodology have been evaluated, respectively, primarily based on which the beneficial situations are: heating temperature 70-90 °C for 20 min, pH 7.0-10, urea focus 2-Four mol/L in regular organic buffers.

 

The recombinant NM generated through the one-step heating methodology held the potential features with self-assembling into sphere nanoparticles with easy morphology.

 

Conclusions: The one-step heating methodology launched right here effectively solubilizes IBs beneath comparatively delicate situations in comparison with the standard ones, which is perhaps essential for the downstream functions; nonetheless, this protocol needs to be pursued fastidiously when it comes to urea-induced modification delicate functions.

 

Additional, this methodology will be utilized beneath broad buffer, pH and temperature situations, conferring the potential to use to different thermal steady proteins.

 

Key phrases: Heating; Inclusion physique solubilization; NM IBs; Recombinant spidroin.

Antibody for Human GRP78 (Bip)

SPC-180C 0.025mg
EUR 216
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is unconjugated.

Antibody for Human GRP78 (Bip)

SPC-180D 0.1mg
EUR 392.4
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is unconjugated.

Antibody for Human GRP78 (Bip)

SPC-180D-A390 0.1mg
EUR 448.8
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 390.

Antibody for Human GRP78 (Bip)

SPC-180D-A488 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 488.

Antibody for Human GRP78 (Bip)

SPC-180D-A565 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 565.

Antibody for Human GRP78 (Bip)

SPC-180D-A594 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 594.

Antibody for Human GRP78 (Bip)

SPC-180D-A633 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 633.

Antibody for Human GRP78 (Bip)

SPC-180D-A655 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 655.

Antibody for Human GRP78 (Bip)

SPC-180D-A680 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 680.

Antibody for Human GRP78 (Bip)

SPC-180D-A700 0.1mg
EUR 447.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to ATTO 700.

Antibody for Human GRP78 (Bip)

SPC-180D-ALP 0.1mg
EUR 440.4
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human GRP78 (Bip)

SPC-180D-APC 0.1mg
EUR 446.4
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to APC .

Antibody for Human GRP78 (Bip)

SPC-180D-APCCY7 0.1mg
EUR 534
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to APC/Cy7.

Antibody for Human GRP78 (Bip)

SPC-180D-BI 0.1mg
EUR 442.8
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Biotin.

Antibody for Human GRP78 (Bip)

SPC-180D-DY350 0.1mg
EUR 465.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Dylight 350.

Antibody for Human GRP78 (Bip)

SPC-180D-DY405 0.1mg
EUR 451.2
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Dylight 405.

Antibody for Human GRP78 (Bip)

SPC-180D-DY488 0.1mg
EUR 439.2
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Dylight 488.

Antibody for Human GRP78 (Bip)

SPC-180D-DY594 0.1mg
EUR 441.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Dylight 594.

Antibody for Human GRP78 (Bip)

SPC-180D-DY633 0.1mg
EUR 435.6
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Dylight 633.

Antibody for Human GRP78 (Bip)

SPC-180D-FITC 0.1mg
EUR 438
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to FITC.

Antibody for Human GRP78 (Bip)

SPC-180D-HRP 0.1mg
EUR 433.2
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to HRP.

Antibody for Human GRP78 (Bip)

SPC-180D-P594 0.1mg
EUR 456
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to PE/ATTO 594.

Antibody for Human GRP78 (Bip)

SPC-180D-PCP 0.1mg
EUR 446.4
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to PerCP.

Antibody for Human GRP78 (Bip)

SPC-180D-RPE 0.1mg
EUR 444
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to RPE .

Antibody for Human GRP78 (Bip)

SPC-180D-STR 0.1mg
EUR 445.2
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is conjugated to Streptavidin.

Antibody for Human GRP78 (Bip)

SPC-180S 0.012mg
EUR 78
Description: A polyclonal antibody for GRP78 from Human | Mouse | Rat | Dog | Fruit Fly (Drosophila melanogaster) | Hamster. The antibody is produced in rabbit after immunization with Human Full length human GRP78 (Bip) his tagged at the N terminus. The Antibody is tested and validated for WB, IHC, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:2000), ICC/IF (1:100). This GRP78 antibody is unconjugated.

GRP78 / BIP Antibody

abx233662-100ug 100 ug
EUR 610.8

GRP78 Bip Antibody

39220-100ul 100ul
EUR 468

GRP78 BiP Antibody

abx038413-100ug 100 ug
EUR 469.2

GRP78 BiP Antibody

48115-100ul 100ul
EUR 399.6

GRP78 BiP Antibody

48115-50ul 50ul
EUR 286.8

GRP78 BiP Antibody

48119-100ul 100ul
EUR 399.6

GRP78 BiP Antibody

48119-50ul 50ul
EUR 286.8

GRP78 Antibody / BiP

F54005-0.1ML 0.1 ml
EUR 379
Description: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

GRP78 Antibody (BiP)

R36415-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: HSPA5; Heat shock 70kDa protein 5; glucose-regulated protein 78

GRP78 Antibody (BiP)

R36416-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: HSPA5; Heat shock 70kDa protein 5; glucose-regulated protein 78

BiP Antibody GRP78

R30913 100 ug
EUR 356.15
Description: HSPA5 (heat shock 70kDa protein 5) also known as glucose-regulated protein, 78kD(GRP78) or BiP, is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum.BiP is an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by theproteasome. Shen et al.(2002)concluded thatBiPretains ATF6 in the ER by inhibiting its Golgi localization signals and that dissociation ofBiPduring ER stress allows ATF6 to be transported to the Golgi. The findings ofShen et al.(2002)demonstrated thatthe proteinis a key element in sensing the folding capacity within the ER.

Be First to Comment

Leave a Reply

Your email address will not be published.